ABSTRACT
Las infecciones por hongos son una causa de morbilidad y mortalidad, lo que lleva a un incremento de la estancia hospitalaria y a un aumento de los costos en salud, en el período neonatal. Durante este período, los prematuros son los más afectados. Las especies Candida son la causa principal de infección fúngica. La mayoría son causadas por C. albicans, C. parapsilosis, C. glabrata y C. tropicalis, aunque otras especies han sido reportadas. Una de ellas, como un patógeno emergente, es K. ohmeri. Este organismo ha sido reportado como patógeno en el período neonatal, principalmente en prematuros. Los factores de riesgo asociados a infección fúngica son accesos venosos centrales, inmunosupresión, larga estancia hospitalaria, intubación endotraqueal y uso de antibióticos. Presentamos a un neonato con una masa mediastinal, quien requirió múltiples intervenciones, como pericardiocentesis, catéter central, ventilación mecánica y antibióticos. Durante su evolución, presentó infección por K. ohmeri. Fue tratado con anfotericina B, con evolución clínica satisfactoria.
Invasive fungal infections are a considerable cause of morbidity, mortality, increased hospital stay durations, and high health care costs, during neonatal period. In this period, the premature infants are the most affected. Candida species are the leading cause of invasive fungal infections. The majority of neonatal Candida infections are caused by C. albicans, C. parapsilosis, C. glabrata and C. tropicalis, although other fungus species are being reported. One such emerging pathogen is K. ohmeri. This organism has been reported as a pathogen in the neonatal period, principally in premature infants. The risk factors associated with fungal infection are central line, immunosuppression, prolonged hospital stay, endotracheal intubation and exposure to antibiotics. We present a term baby with a mediastinal mass, who required several procedures, as pericardiocentesis, central catheters, mechanical ventilation, antibiotics. During his evolution, he presented infection by K. ohmeri. The baby was treated with amphotericin B, with satisfactory clinical course.
Subject(s)
Humans , Male , Infant, Newborn , Saccharomycetales , Mediastinum , Mycoses/diagnosisABSTRACT
OBJECTIVE To understand the factors of mycotic pharyngitis or stomatitis for patients after tracheotomy,especially related to antibiotic.METHODS Seventy patients after tracheotomy were divided into two groups.In each group,the clinical data,risk factors and culture results of oral cavity were analyzed.RESULTS The time,kind,dose,way,and combined use of antibiotic were all related to mycotic pharyngitis or stomatitis.CONCLUSIONS The longer time,the complex kind,the larger dose,and the combined use of antibiotic are all delayed patients recovering.
ABSTRACT
OBJECTIVE:To study the relation between mycotic superinfections and use of antimicrobials in senile patients.METHODS:106 senile in-patients who had mycotic superinfections following administration of antimicrobials were retrospectively analysed.RESULTS:Most of the senile patients over 60 years of age had severe underlying diseases and hypoimmunity and needed staying hospital for long time.Antimicrobial-induced mycotic superinfection played an important role in leading to mycotic infection in hospital accounting for 84.6% of total mycotic infections in our hospital during the corresponding period.Pulmonary infection was the commonest one and urinary tract infection the next.CONCLUSION:Long-term use of broad-spectrum antimicrobials is the main contributing factor resulting in increase of mycotic superinfections of senile patients in hospital.